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Clair, C., Cohen, M

Interestingly, studies have shown that a possible mechanism for the regulation of HDC activity is the change of histidine itself or the concentration of various compounds that affect HDC activity

"Carpal tunnel syndrome pathophysiology: role of subsynovial connective tissue"

Copper is also directed to the mitochondria, where it is used by cytochrome c oxidase (COX) to activate the activity of enzymes in the respiratory chain